tag:blogger.com,1999:blog-3045634714760830992.post7660812180402401143..comments2023-06-05T11:51:38.383-04:00Comments on Evolutionary Psychiatry: That O6/O3 Ratio, Still ImportantAnonymoushttp://www.blogger.com/profile/04429177284200775781noreply@blogger.comBlogger8125tag:blogger.com,1999:blog-3045634714760830992.post-68706584955429757752013-08-27T15:44:17.744-04:002013-08-27T15:44:17.744-04:00"...if you look at PUFA O3:O6 in the red bloo..."...if you look at PUFA O3:O6 in the red blood cell plasma membranes, which is felt to be a marker of the bodily PUFA ratio in general..."<br /><br />Is it better to test red blood cell membranes or plasma for fatty acids?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-74655063172895100222011-04-02T12:52:16.270-04:002011-04-02T12:52:16.270-04:00Tony, it is interesting the way they were able to ...Tony, it is interesting the way they were able to find some linear differences. It's just an observational study, however, so take it for what it is worth.<br /><br />I agree as to the testing - was reading a recent article about ADHD studies and the issues with cognitive testing versus real-life situations and the problems that imposed on research. However, for basic executive functioning the tests they used in this study weren't too bad. It is actually similar to what I do in my office as a screen for dementia (I typically do digit span forward and backwards, clock drawing, copy a complicated figure, other tests of memory, F words and animal words, continue/complete a pattern, those sorts of things. But when I send someone out for neuropsych testing, I expect a long and detailed report!Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-30284207432221936302011-04-02T12:08:09.172-04:002011-04-02T12:08:09.172-04:00Dr. Deans,
thanks for the info; it is about what ...Dr. Deans,<br /><br />thanks for the info; it is about what I expected. Of course, in the absence of effort testing - a condition which affects virtually all of cognitive testing, both clinical, and especially research based - there is no way to know if the obtained data were affected, and if so, how much, by "lack of effort." <br /><br />Moreover, since the tests that were used are not specific for cognitive impairment (save for Trail-Making), or have limited such specificity, but instead are subject to very high sensitivity to multiple independent variables, I would for one not trust at all the conclusions drawn by the experimenters. <br /><br />Just the view of a traditionally trained neuropsychologist who was taught that if you are going to evaluate the condition of the brain by way of psychological tests, then those tests should be highly specific for brain function while minimally sensitive to such things as depression, anxiety. As a currently trained neuropsychologist, it is increasingly regarded as a failure to meet the standard of care to omit tests of effort whether in clinical, forensic or research contexts.<br /><br />Keep up the good work on your site. It is of substantial value to me and to my other colleagues and patients as well.<br /><br />tonyAnthony Semone, PhDhttps://www.blogger.com/profile/17670520148814089976noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-56560591804542355332011-04-02T11:09:52.389-04:002011-04-02T11:09:52.389-04:00Tony - researchers used a variety of standard test...Tony - researchers used a variety of standard tests - stroop coulor word test, boston naming test, RAVLT, how many F or S words or words not containing E,A can you name in 60 seconds, digit span forward and backwards, trail-making, letter-number sequencing tests, some administered immediately, some testing delayed recall, then also standard depression, physical health, and mental health scales. It wasn't as exhaustive as some I've seen (some RCT omega3 trials used more intensive testing), but it wasn't bad and should be able to catch mild cognitive impairment and gradations thereof.Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-47786526855316994032011-04-01T20:26:22.833-04:002011-04-01T20:26:22.833-04:00Tony - If I have a moment tomorrow I'll be mor...Tony - If I have a moment tomorrow I'll be more detailed, but they did extensive cognitive testing. I have the full text printed out but it is downstairs somewhere. Usually these dementia studies are fairly rigorous. It's the medical literature and not the typical useless study you see in the nutrition literature. (hmmm that was cranky. Oh well). <br /><br />Ted - Who is to say? There's genetics, then epigenetics, then stress, sleep, temperament, experience, then diet... However, I would say we are likely born less broken than not?Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-5742423647002911952011-04-01T18:33:25.141-04:002011-04-01T18:33:25.141-04:00@tony -- go to a university nearby to obtain the f...@tony -- go to a university nearby to obtain the full version. Usually it can't be found for free. <br /><br />Dr Deans:<br />You wisely point out that many mental conditions are caused by poor nutrition. It makes me wonder, how much is due to nutrition and stress, and how much (if any) due to simple genetics? Can stress relief, proper sleep and a paleo diet be the ultimate fix? Or am I just too idealistic? <br />A definitive answer is probably impossible, but I'd like to hear your thoughts.Tedhttps://www.blogger.com/profile/11395086301125030514noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-64246578908604552122011-04-01T17:33:25.274-04:002011-04-01T17:33:25.274-04:00Dr. Deans,
do you have a link to the full article...Dr. Deans,<br /><br />do you have a link to the full article? I get only the abstract and it doesn't include any information as to how "cognitive impairment" was measured. <br /><br />H. Anthony Semone, PhD<br />Clinical NeuropsychologistAnthony Semone, PhDhttps://www.blogger.com/profile/17670520148814089976noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-78697026994965753102011-04-01T14:29:20.900-04:002011-04-01T14:29:20.900-04:00I love the quarterback analogy!
Do you ever get t...I love the quarterback analogy!<br /><br />Do you ever get the feeling that 'we' (the paleo bunch) have developed some extra perception and cognitive powers? I find the more I read and study the more blindingly obvious that everything comes back to diet, just everything. I wonder, perhaps it's the balance of 03:06 in our brains :-)Cavegirlhttps://www.blogger.com/profile/02319318255360473712noreply@blogger.com