tag:blogger.com,1999:blog-3045634714760830992.post1933208793590037329..comments2023-06-05T11:51:38.383-04:00Comments on Evolutionary Psychiatry: Folate! The Beginning.Anonymoushttp://www.blogger.com/profile/04429177284200775781noreply@blogger.comBlogger36125tag:blogger.com,1999:blog-3045634714760830992.post-49698305522422142332014-07-09T19:49:56.515-04:002014-07-09T19:49:56.515-04:00These guys claim this is very similar to Deplin 15...These guys claim this is very similar to Deplin 15 and it is less than a dollar a pill. Anyone else know anything about the company or their claims? http://www.methyl-life.com/methylfolate-15.html#ModernArtshttps://www.blogger.com/profile/07816229492907646583noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-34378026687036470572014-07-09T00:03:52.626-04:002014-07-09T00:03:52.626-04:00Brand or website source for something comparable t...Brand or website source for something comparable to Deplin 15? Taking 19 800 mcg little pills seems cumbersome plus you seem to need to spread them out throughout the day. Thanks.ModernArtshttps://www.blogger.com/profile/07816229492907646583noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-2293574406053747532014-06-24T11:35:09.690-04:002014-06-24T11:35:09.690-04:00I have to comment about the insurance aspect of ta...I have to comment about the insurance aspect of taking deplin. I took deplin in 2011 and 2012 and insurace DID cover it. Additionally, there is a generic version of the prescription as well. Deplin is $80, l-methylfolate calcium is $10. My insurance covered both forms. Jenn Tylerhttps://www.blogger.com/profile/16459532628986572723noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-45598727127067423902014-05-23T00:50:14.902-04:002014-05-23T00:50:14.902-04:00I take Deplin and find it life changing. My son w...I take Deplin and find it life changing. My son who is a teen had similar problems with his stomach and extreme tiredness and irratability that I did. I have given him OTC methyl folate and on the days he takes it he is markedly different. I would like to find a physician to prescribe deplin for him too. No one around here even knows what it is. I had to go to a doc three hours away and willing to go away for my son also. How do I find a pediatric doc that knows about deplin?Anonymoushttps://www.blogger.com/profile/00630916444032494520noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-42046235095706040132014-04-28T12:25:11.633-04:002014-04-28T12:25:11.633-04:00This comment has been removed by the author.Anonymoushttps://www.blogger.com/profile/01488861720191193084noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-90099489121590199082014-01-09T10:09:29.272-05:002014-01-09T10:09:29.272-05:00Two possible reasons:
a) folic acid can (besides ...Two possible reasons:<br /><br />a) folic acid can (besides masking the blood signs of B12 deficiency) also worsen B12 deficiency symptoms<br />b) as mentioned in this article, folic acid may actually reduce the efficacy of methylfolate.<br /><br />So you should likely be taking a methylfolate supplement together with an active form of B12 (methylcobalamin).M.https://www.blogger.com/profile/17982894362182079013noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-72111100985253362542013-12-24T11:32:40.535-05:002013-12-24T11:32:40.535-05:00Hi! Great blog and article. I have a question thou...Hi! Great blog and article. I have a question though: why does folic acid makes me depressed? I have diagnosed major depression + anxiety (although mixed biploar was suspected in the past)and doing somewhat better on effexor+neurontin. I've read of the usefullness of folate in depression but each time I try taking it I get severely depressed. This is the case regardless of dose and brand, and even multivitamins with folic acid have this effect. It was the same when I tried folic acid before being put on meds, so interactions aren't the problem either. Any thoughts?Shadowpigmenthttps://www.blogger.com/profile/17802252736271082391noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-48251315111595485212013-11-01T12:57:46.010-04:002013-11-01T12:57:46.010-04:00Cath,
I, too, need the name of the supplement comp...Cath,<br />I, too, need the name of the supplement company you mentioned.<br />TYswraterhttps://www.blogger.com/profile/06043904470062810633noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-46395880989790376322013-10-27T18:20:00.711-04:002013-10-27T18:20:00.711-04:00Hi Emily. Do u know if the MTHFR enzyme is really ...Hi Emily. Do u know if the MTHFR enzyme is really involved in the BH4 cycle??Bobhttps://www.blogger.com/profile/09000826860203116695noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-92056452618957121432013-10-03T16:21:09.654-04:002013-10-03T16:21:09.654-04:00cath I need the name of that company that has the ...cath I need the name of that company that has the supplement without the fillers , and do you know if it is for MTHFR people who can not break down the folic acid on their own and if the product is already broken down like Deplin is , I am alergic to some of the ingredients they use as fillers and need a quick alternative ty Anonymoushttps://www.blogger.com/profile/13405272396674287313noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-14953131832718061182013-08-28T11:41:57.138-04:002013-08-28T11:41:57.138-04:00I have BXBS and it's a good policy, but it is ...I have BXBS and it's a good policy, but it is not covered by my insurance...sad. It has improved my depression significantly. I suffered from depression for 15 years with no real relief until starting the Deplin 8 mounths ago...what a life saver. It would have been great if I had had a Dr. who knew about it sooner. pamshttps://www.blogger.com/profile/11766556581886281605noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-2015043570092307142013-07-19T23:23:12.562-04:002013-07-19T23:23:12.562-04:00I never understood Deplin. My son needed tons of 5...I never understood Deplin. My son needed tons of 5-mthfr and we used a well regarded, monitored supplement company. They produced a product not laced with fillers and additives. $30/mo for his very high dose. Cathhttps://www.blogger.com/profile/01435442111515018101noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-90372028437833327042013-05-12T18:47:14.933-04:002013-05-12T18:47:14.933-04:00Emily,
This is interesting to me. I have anxiety a...Emily,<br />This is interesting to me. I have anxiety and mild case of ocd (more obsessive) and doc suggested that i get on folic acid in addition to two ssri's i am currently taking and have been for years. I have only been on 1 mg for a few days and my mood has gotten more sad, and i am feeling worse. Could it be a possibility that folic acid is causing this problem? I dont know if its the folic acid or my imagination.Jesuschickhttps://www.blogger.com/profile/00026468170832597354noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-5645194914167828082013-04-25T20:36:31.700-04:002013-04-25T20:36:31.700-04:00I'm in complete agreement. Pamlab has much to...I'm in complete agreement. Pamlab has much to gain with Deplin as a "medicianl food". Education regarding this supplement is crucial.plylehttps://www.blogger.com/profile/12815196155992115607noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-60545230775663006532013-04-25T20:27:22.050-04:002013-04-25T20:27:22.050-04:00The most recent studies show that 7.5 does not get...The most recent studies show that 7.5 does not get the desired effect. 15 mg is required.plylehttps://www.blogger.com/profile/12815196155992115607noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-41330758884314550752012-12-15T15:56:59.790-05:002012-12-15T15:56:59.790-05:00Dr. Deans wrote: "So if you prescribe medicat...Dr. Deans wrote: "So if you prescribe medications meant to maximize the efficiency of neurotransmitter* transmission...." <br /><br />Now that "chemical imbalance" is an embarrassment, is this the current rationalization for psychiatric drugs? Maximizing efficiency of transmission? Is there any evidence for this? Thought not.<br /><br />I read the 5-MTHF findings of M. Fava etc. differently: That people with low B-12 or folate status are being diagnosed with psychiatric disorders and treated with drugs that do not address the nutritional problem. The nutritional deficiency worsens while inappropriate therapy is pursued (overall health risks also increase because of the medication).<br /><br />These people naturally perk up when an appropriate nutritional supplement is added.<br /><br />M. Fava etc. should be writing an apologia to the millions misdiagnosed and treated psychiatrically for physiological conditions. Instead, he's published infomercials for Deplin as an "add-on" to vastly profitable psychiatric drugs.<br /><br />M. Fava was hired by Deplin's manufacturer (see Completed Trials http://www.pamlabrd.com/clinical-trials ) to produce papers touting this brand-name 5-MTHF.<br /><br />There is nothing special about the 5-MTHF in Deplin. 5-MTHF supplements have long been available at lower cost from other manufacturers to treat those with the MTHFR genetic variation affecting folate metabolism. (I am one of those people, and I was misdiagnosed and treated with Paxil, which effectively has destroyed my life.)<br /><br />By calling Deplin a "medical food" available by prescription, it can be reimbursed by health insurance and Medicare. This is enormously profitable to Pamlab, Deplin's manufacturer. Brand-name 5-MTHF Deplin is a health insurance scam.<br /><br />I am very disappointed in you, Dr. Deans.<br /><br />Survivinghttps://www.blogger.com/profile/17594002730059627754noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-60792740520715795982011-12-21T20:16:07.108-05:002011-12-21T20:16:07.108-05:00This comment has been removed by the author.Ssplashhttps://www.blogger.com/profile/08122622888244064160noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-13330036940663895252011-12-21T20:13:11.663-05:002011-12-21T20:13:11.663-05:00This comment has been removed by the author.Ssplashhttps://www.blogger.com/profile/08122622888244064160noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-11687593949355542592011-10-06T14:15:14.180-04:002011-10-06T14:15:14.180-04:00Facinating post. From 23andme I found I am heterog...Facinating post. From 23andme I found I am heterogeneous for C677T, giving me a 65%~ of normal ability to make the MTHFR enzyme. As someone who has nearly always suffered from (mild but persistent) depression (even on a paleo diet), I am wondering if this could be a key piece of the puzzle. I'm having my homocysteine levels tested soon and will also consider supplementing.Andyhttps://www.blogger.com/profile/14845542664718113799noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-83653863766646075422011-08-29T19:03:02.440-04:002011-08-29T19:03:02.440-04:00I read two articles about the importance of micron...I read two articles about the importance of micronutrients:<br /><br />http://www.lef.org/magazine/mag2011/aug2011_Interview-with-Dr-Bruce-Ames_01.htm<br /><br />http://www.sciencedaily.com/releases/2011/05/110531115323.htm<br /><br />From the second:<br />Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal. "As this report shows, taking a multivitamin that contains selenium is a good way to prevent deficiencies that, over time, can cause harm in ways that we are just beginning to understand."<br /><br />After reading this post I am not sure about multivitamins, also most do not have good quality mineral salts or all the variants of a vitamin e.g. only alpha tocopherol.<br /><br />Anyway, I frequently take a multi, especially for the Bs. Not sure if I am doing right.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-67559294524750247512011-08-28T22:32:14.556-04:002011-08-28T22:32:14.556-04:00Emily, you may interested in reading this blog pos...Emily, you may interested in reading this blog post at the SCM Blog. After reading the post, I was wishing I could find a multi that did not contain Folic Acid.<br /><br />http://www.sciencebasedmedicine.org/index.php/the-benefits-and-risks-of-folic-acid-supplementation/<br /><br />Here is an excerp:<br /><br />Could a vitamin with proven benefits in one group cause harm to another? That’s the growing concern with folic acid, the vitamin that dramatically reduces the risk of neural tube birth defects such a spina bifida. Studies designed to explore the possible benefits of folic acid for heart disease, stroke and cancer are giving out some worrying signs: At best, folic acid is ineffective, and at worst it may be increasing the risks of some cancers. So what does this say about routine supplementation for the typical healthy individual, and its overall risk and benefit?Nickhttps://www.blogger.com/profile/05352151855145958818noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-1038974221199387802011-08-28T21:54:56.565-04:002011-08-28T21:54:56.565-04:00Wow. I didn't know folate and folic acid are n...Wow. I didn't know folate and folic acid are not the same. As always, whole foods are the way to go.<br /><br />I wrote in my blog about beans, the most consumed food here in Brazil (actually, rice and beans). With a recipe of brazilian beans included, I looove it :-)<br /><br />http://tinkeringwithnutrition.blogspot.com/2011/08/lovely-beans-wonderful-beans-recipe.htmlEzerhttps://www.blogger.com/profile/02373617761960602053noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-61195737179623598822011-08-28T12:50:55.983-04:002011-08-28T12:50:55.983-04:00Good point, strake. A quick look at nutritiondata....Good point, strake. A quick look at nutritiondata.com suggests that liver has 50% more folate than spinach, by weight. And it's rich in B12 too!Captain Mikeehttps://www.blogger.com/profile/16275482085057683749noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-70413672992795238902011-08-28T00:15:03.213-04:002011-08-28T00:15:03.213-04:00I wonder if the masking affects of folic acid is w...I wonder if the masking affects of folic acid is what allows some vegans to get by on B12 deficit for a while?David Csonkahttps://www.blogger.com/profile/15158978883756798591noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-1918110313556766132011-08-27T23:07:08.542-04:002011-08-27T23:07:08.542-04:00Emily, which lab tests do you recommend to your pa...Emily, which lab tests do you recommend to your patients? Thanks.Anonymousnoreply@blogger.com