tag:blogger.com,1999:blog-3045634714760830992.post781756233172938333..comments2023-06-05T11:51:38.383-04:00Comments on Evolutionary Psychiatry: Zinc RevolutionAnonymoushttp://www.blogger.com/profile/04429177284200775781noreply@blogger.comBlogger12125tag:blogger.com,1999:blog-3045634714760830992.post-89150582688517070002011-09-10T04:09:10.337-04:002011-09-10T04:09:10.337-04:00A very late question here, but I found this post ...A very late question here, but I found this post by searching for zinc and copper on your site. <br /><br />Where do you stand on pyroluria (aka Kryptopyroluria (KPU)/pyroluria hydroxyhaemopyrrollactumuria (HPU))? People with this little-known condition are extremely deficient in zinc and B6 and are often helped by mega doses of both.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-23815395182191362302010-10-17T19:31:43.832-04:002010-10-17T19:31:43.832-04:00There have been deaths from copper deficiency from...There have been deaths from copper deficiency from zinc adhesives! I do not recommend huge overdoses of zinc.Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-4773891456104337132010-10-17T17:52:57.967-04:002010-10-17T17:52:57.967-04:00What about neuropathy caused by too much zinc in d...What about neuropathy caused by too much zinc in denture adhesives?dlmhttps://www.blogger.com/profile/06309957281983807032noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-34219513155380228192010-10-12T07:27:43.856-04:002010-10-12T07:27:43.856-04:00DM - as I understand it Eaton revamped his conclus...DM - as I understand it Eaton revamped his conclusions in 2000 (according to Gary Taubes in GCBC) because, believe it or not, they didn't count organ meats or marrow in the earlier papers, which frankly boggles *my* mind. I've looked for the primary source on this correction(with a few google and pubmed searches, though not for too terribly long) and couldn't find anything. If anyone has a primary source on this correction, I'd love to see it! Maybe I should get cordain's updated Paleo Diet cookbook as it seems to be less fat phobic and would presumably include the correction. And I don't think most of us need quite so much zinc. I think 20-25 mg daily seems like a more reasonable number. Copper deficiency is a real issue with modern diets too, apparently.Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-80487339425460071912010-10-12T03:44:52.673-04:002010-10-12T03:44:52.673-04:00Thanks Emily that's great, although the mind s...Thanks Emily that's great, although the mind still boggles at eating up to 3.5g protein/KG! It's also a shame that they recommend 7-8% SFA and no more than 25% energy from fat. I can't help but think that both of these odd conclusions would make more sense if they were to assume that HG's ate fattier game.David Mosshttps://www.blogger.com/profile/08508780038542342811noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-21764202660019119022010-10-11T10:33:37.274-04:002010-10-11T10:33:37.274-04:00Hi DM - I orginally got the number 43 from "P...Hi DM - I orginally got the number 43 from "Primal Body, Primal Mind" but her primary source for the table was this paper:<br /><br />http://www.direct-ms.org/pdf/EvolutionPaleolithic/Eaton%20Paleo%20Nutri%20Review%20EJCN.pdf<br /><br />It's in table 3, and Eaton et al discuss their methods. I think the main thing to keep in mind is that HGs eat a lot more than we do. Average is 3000 calories. It is much easier to get plenty of vitamins and minerals when you eat a lot of nutrient rich whole real foods. On a modern calorie-restricted, less moving around sort of diet, it is easy to get deficient in something unless you are pretty meticulous.Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-68962434395865870122010-10-11T04:29:35.322-04:002010-10-11T04:29:35.322-04:00Really interesting about the hunter-gatherer zinc ...Really interesting about the hunter-gatherer zinc intake. I'll up my own zinc intake, which previously I'd tried to keep away from the TUL. I'm curious as to where the figures come from, or how the hunter-gatherer's would have managed it though. 40mg+ of zinc a day requires more than 1kg of steak or liver (giving almost 250g protein).David Mosshttps://www.blogger.com/profile/08508780038542342811noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-43558365150345156902010-10-10T20:54:48.878-04:002010-10-10T20:54:48.878-04:00Gads, the SAD numbers are low! There is a lot mor...Gads, the SAD numbers are low! There is a lot more data on zinc and depression, but there is a lot more theory to suggest at least having replete magnesium stores would be even more important than zinc. I know why magnesium hasn't been studied more - zinc can be tested with a simple blood test. With magnesium you have to follow serial 24 hour urines to make sure research subjects are compliant and magnesium levels are growing in the body, as the serum levels are nearly meaningless (outside an ICU situation).<br /><br />Anyway, I don't see anything wacky or out to lunch or particularly alternative about recommending at least adequate zinc and magnesium. And I hope that magnesium is studied more vigorously. (zinc too, but at least there are research factions doing their thing and churning out papers).Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-38185155502537790132010-10-10T04:55:50.070-04:002010-10-10T04:55:50.070-04:00Interesting numbers from one of Prof Cordain's...Interesting numbers from one of Prof Cordain's looking at nutrient content in a modern diet based on Paleo foods;<br /><br />Magnesium - 643mg (207% of RDA)<br />Zinc - 27.4mg (228% of RDA)<br /><br />In his book, The Paleo Diet, he gives the micronutrient intake numbers based on the typical American Diet;<br /><br />Magnesium - 128mg<br />Zinc - 3.9mg<br /><br />And as the sample diet he uses still includes some meat, perhaps a poor vegetarian/vegan diet is lower still?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-82780244010761421502010-10-09T22:40:38.178-04:002010-10-09T22:40:38.178-04:00That's good to hear, thank you. I eat paleo, s...That's good to hear, thank you. I eat paleo, so enough animal sources, I think I will take the minerals only every other day, as I eat pretty well otherwise.autsajderhttps://www.blogger.com/profile/10603833143691595524noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-83610318372234182792010-10-09T21:35:42.168-04:002010-10-09T21:35:42.168-04:00Autsajder - in the experiments and papers where a ...Autsajder - in the experiments and papers where a zinc supplement amount is named or recommended, it is usually 12- 14mg or thereabouts. Assuming a non-vegetarian diet, total would be around 25mg daily? This would be higher than the RDA but not a mega -dose or anything. I haven't read anything about anxiety. Neurochemically it is extremely similar to depression. All the supplement studies were quite small, so nothing to hang your hat on. The overall lesson as I see it is to have enough zinc on board so you bounce back quickly from the stress-wasting, but there is no need for people without absorption problems or metabolic issues dealing with zinc to take mega doses.Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-17047228738387683742010-10-09T20:50:17.837-04:002010-10-09T20:50:17.837-04:00This is fascinating! And I thought Zinc was good o...This is fascinating! And I thought Zinc was good only for acne ;-)<br />I do battle with depression, even though not severe. I just started taking mix-minerals caps, which have 15mg of Zinc (chelate). I am wondering now if that's enough of a kick or maybe I should get extra Zinc. I am already taking extra Mg (also chelate). I don't like taking too many pills, but prefer the supplements than serious anti-depressants and anti-anxiety meds I have to take now! <br /><br />Do you know if Zinc has similar positive influence on anxiety? Or other mental disorders?<br /><br />oh, and I feel good that such Zinc-obsessed people are coming from my country! :)autsajderhttps://www.blogger.com/profile/10603833143691595524noreply@blogger.com