tag:blogger.com,1999:blog-3045634714760830992.post7559165610533008454..comments2023-06-05T11:51:38.383-04:00Comments on Evolutionary Psychiatry: What the Heck Is an ApoE and Other Stories of How Cholesterol Is Good for YouAnonymoushttp://www.blogger.com/profile/04429177284200775781noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-3045634714760830992.post-52725015202491535322012-12-03T16:32:25.910-05:002012-12-03T16:32:25.910-05:00Hello Mr. Peter M,
I may have read or even have dl...Hello Mr. Peter M,<br />I may have read or even have dl'ed the article already someplace, but what is the source of: -Mark (TIA)<br /><br />"The APOE4 rate in tested parts of India and China comes in at around 5-8%. But more like 50% in remnant hunter gathering populations. Curious."MEJhttps://www.blogger.com/profile/06175420473680473888noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-37196072251970550212011-12-29T00:06:02.416-05:002011-12-29T00:06:02.416-05:00I only post occasionally, but if anyone is looking...I only post occasionally, but if anyone is looking for info on the evolutionary/primal perspective on APOE4, I have a blog on it:<br /><br />http://primale4.wordpress.com/<br /><br />(I am a double E4 carrier). Guest posts, additional authors, and links are all welcome...Patri Friedmanhttps://www.blogger.com/profile/00795471439484698201noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-30720558284128218632010-11-20T10:56:56.170-05:002010-11-20T10:56:56.170-05:00http://www.nutritionandmetabolism.com/content/6/1/...http://www.nutritionandmetabolism.com/content/6/1/31 suggests that ketosis is less effective against Alzheimer's if you have ApoE4.Amber O'Hearnhttps://www.blogger.com/profile/10125813379900433577noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-86698979442000361832010-10-23T11:27:08.057-04:002010-10-23T11:27:08.057-04:00Hi Emily,
Great blog. Just a quick observation. ...Hi Emily, <br /><br />Great blog. Just a quick observation. If the APOE4 allele or 'gene' is so 'inferior' why was it preserved for tens of thousands of years in hunter gathering populations. Quite possibly because it worked very well for them over all that time. Would it not have been weeded out long long ago otherwise? APOE3 has only become dominant 'recently' in the context of a huge shift to a grain-heavy diet practiced by agrarian populations. The APOE4 rate in tested parts of India and China comes in at around 5-8%. But more like 50% in remnant hunter gathering populations. Curious.<br /><br />Maybe APOE4 isn't the demon we think it is. It could be we're just eating the wrong diet--at least for those nearly 30% of us of northern Europeans or African ancestry. If late onset Alzheimer's runs in your family consider getting tested for the APOE4 allele and adjusting your diet accordingly.Peter Mhttps://www.blogger.com/profile/02719233220904261234noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-78214750874121754852010-10-23T05:15:41.022-04:002010-10-23T05:15:41.022-04:00Paul - when I "solve" Alzheimer's fe...Paul - when I "solve" Alzheimer's feel free to link all you want. I will go into the infections as the papers are interesting. The topic takes a lot of explaining biology, so I'm breaking it up into small pieces. <br /><br />Jamie- Dr. Parker linked an article and discussion from his diabetic Mediterranean diet blog "Atkins for diabetes, a lively debate.". Gary Taubes, Robert Su, Richard Feingold, Westmark (I think) and others are weighing in. It's as if the "not scared of fat" people almost speak a different language than the "eek, fat will kill you" people. We've gone a long way down the rabbit hole. <br /><br />The funny thing is, when I talk to people who know a lot about health (especially nurses or ex nurses), many of them seem to secretly believe the low fat paradigm is a bunch of hooey and that we should be eating real, wholesome food. They seem absolutely relieved when I bring the heretical idea to light.Anonymoushttps://www.blogger.com/profile/04429177284200775781noreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-62921697030531484052010-10-22T23:03:53.153-04:002010-10-22T23:03:53.153-04:00"I don't make this stuff up"
You do..."I don't make this stuff up"<br /><br />You don't know how many times I have had to truck that line out in the last few months when it comes to explaining this stuff to people and I invariably get the "what are you smoking" face! You get treated like you might have an overactive imagination when you talk of sunlight being good, saturated fat not causing CVD, wholegrains not being healthy etc.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3045634714760830992.post-67260274137625549892010-10-22T22:56:50.698-04:002010-10-22T22:56:50.698-04:00Nice post, Emily!
I'm thinking that instead o...Nice post, Emily!<br /><br />I'm thinking that instead of doing more Alzheimer's posts, I can just wait for you to solve everything, and put up a link.<br /><br />Unless you end the series before getting to infections ...Paul Jaminethttps://www.blogger.com/profile/15122941682076992645noreply@blogger.com